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Synopsis
Bioreactors are vessels or tanks in which whole cells or cell-free enzymes transform raw materials into biochemical products and/or less undesirable by-products. The microbial cell itself is a miniature bioreactor; other examples include shake flasks, Petri dishes, and industrial fermentors. Diagnostic products based on enzymatic reactions, farm silos for silage fermentations, bread pans with fermenting yeast, and the soil in a Kansas wheat field may also be viewed as bioreactors. While the bioreactor may be simple or highly instrumented, the important consideration is the ability to produce the desired product or result. The bioreactor is designed and operated to provide the environment for product formation selected by the scientist, baker, or winemaker. It is the heart of many biotechnological systems that are used for agricultural, environmental, industrial, and medical applications. Industrial bioreactors may be operated as batch reactors or continuously, aerobically or anaerobically, and with pure or mixed cultures. In many bioreactors, three phases (gas, liquid, and solid) are present and mass transfer is an important consideration. Biofilms and immobilized cells can be used to retain microbial biomass in a flow bioreactor. Sensors, instrumentation, and control systems are essential for industrial bioreactors.Table of Contents
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